El Helalyaالمؤسسة
تاريخ التسجيل : 08/08/2008
| موضوع: Appropriate Dose Selection - How to Optimize Clinical Drug Development (Ernst Scherin الأحد 6 يونيو 2010 - 17:23 | |
| Appropriate Dose Selection - How to Optimize Clinical Drug Development (Ernst Schering Foundation Symposium Proceedings) By J. Venitz, W. Sittner Publisher: Springer Number Of Pages: 222 Publication Date: 2006-11-10 ISBN-10 / ASIN: 3540278672 ISBN-13 / EAN: 9783540278672 Product Description: Optimal dose individualization has become more important in improving clinical efficacy and safety, given the variability in drug response, e.g., due to concurrent illnesses or co-medications. Therefore, the role of optimal dose finding in early clinical drug development so as to maximize successful clinical use is emphasized. The continued use of biomarkers – based on the (known) pharmacology of the drug and/or biology of the underlying disease – along with exposure–response evaluation throughout all phases of drug development can quantitatively integrate clinical pharmacology knowledge, provide early proof of concept, and help in rational dose selection and rational drug product labeling for clinical use [ندعوك للتسجيل في المنتدى أو التعريف بنفسك لمعاينة هذا الرابط] الموضوع : Appropriate Dose Selection - How to Optimize Clinical Drug Development (Ernst Scherin المصدر :منتديات تقى الإسلامية الكاتب: El Helalya |
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الجنه تنادينيالاشراف العام
تاريخ التسجيل : 16/05/2010
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واسلاماهالمراقبة العامة
تاريخ التسجيل : 23/06/2009
| موضوع: رد: Appropriate Dose Selection - How to Optimize Clinical Drug Development (Ernst Scherin الجمعة 8 يوليو 2011 - 19:36 | |
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